Barbara-Anne Battelle Publications

Florini, J. R., Brivio, R. P., and Battelle, B-A.: Isoelectric focusing of myosin in dilute polyacrylamid gels. Anal. Biochem. 4: 345-350, 1971.

Battelle, B-A., and Florini, J. R.: Protein synthesis in chicken muscular dystrophy.  Biochemistry. 12:637-654, 1973.

Florini, J. R., Brivio, R. P., and Battelle, B-A.: Isoelectric focusing of muscle proteins.  Ann. NY Acad. Sci. 209: 299-310, 1973.

LaVail, M. M., and Battelle, B-A.: Influence of eye pigmentation and light deprivation on inherited retinal dystrophy in the rat.  Exp. Eye Res. 21: 167-192, 1975.

Kravitz, E. A., Evans, P. D., Talamo, B. R., Wallace, B. G., and Battelle, B-A.: Octopamine neurons in lobsters: location morphology, release of octopamine and possible physiological role.  Cold Spring Harbor Symp. Quant. Biol. XL, “The Synapse”, 127-133, 1976.

Kravitz, E. A., Battelle, B-A., Evans, P. D., Talamo, B. R., and Wallace, B. G.: Octopamine neurons in lobsters.  In Ferrendelli, J. A., McEwen, B. S. and Synder, S. H. (Eds.): Neuroscience Symposium, Vol. 1, 67-81, 1976.

Battelle, B-A., and Kravitz, E. A.: Targets of octopamine action in the lobster: Cyclic nucleotide changes and physiological effects.  J. Pharmacol. Exp. Ther. 205: 438-448, 1978.

Battelle, B-A., and LaVail, M. M.: Rhodopsin content and rod outer segment length in albino rat eyes:  Modification by dark adaption.  Exp. Eye Res. 26: 487-497, 1978.

Battelle, B-A., Kravitz, E. A., and Stieve, H.: Neurotransmitter synthesis in Limulus ventral nerve photoreceptors. Experientia. 35: 778-780, 1979.

Battelle, B-A. and LaVail, M. M.: Protein synthesis in retinas of rats with inherited retinal dystrophy.  Exp. Eye Res. 31: 251-269, 1980.

Battelle, B-A.: Neurotransmitter candidates in the visual system of Limulus polyphemus: Synthesis and distribution of octopamine.  Vision Res. 20: 911-922, 1980.

Puro, D. G., Battelle, B-A., and Hansmann, K. E.: Development of cholinergic neurons in rat retina. Devel. Biol. 91: 138-148, 1982.

Kaupp, U. B., Malbon, C. C., Battelle, B-A., and Brown, J. E.: Octopamine stimulated rise in cAMP in Limulus ventral photoreceptors. Vision Res. 22: 1503-1506, 1982.

Battelle, B-A., Evans, J. A., and Chamberlain, S. C.: Efferent fibers to Limulus eyes synthesize and release octopamine.  Science. 216: 1250-1252, 1982.

Evans, J. A., Chamberlain, S. C, and Battelle, B-A.: Autoradiographic localization of newly-synthesized octopamine to retinal efferents in the Limulus visual system.  J. Comp. Neurol. 219: 369-383, 1983.

Yeh, H. H., Battelle, B-A., and Puro, D. G.: Maturation of neurotransmission at cholinergic synapses formed in culture by rat retinal neurons: Regulation by cyclic AMP.  Dev. Brain Res. 10: 63-72, 1983.

Battelle, B-A., and Evans, J. A.: Octopamine release from centrifugal fibers of the Limulus visual system.  J. Neurochem. 42: 71-79, 1984.

Chamberlain, S. C, Battelle, B-A., and Calman, B. G.: Subcellular localization of neutral red staining in Limulus ventral photoreceptors.  J. Neurobiol. 15: 79-86, 1984.

Battelle, B-A.: Efferent innervation to Limulus eyes.  Trends in Neuroscience. 7: 277-282, 1984.

Yeh, H. H., Battelle, B-A., and Puro, D. G.: Dopamine regulates synaptic transmission mediated by cholinergic neurons of the rat retina.  Neuroscience. 13: 901-909, 1984.

Engbretson, G. A. and Battelle, B-A.: Identification of putative neurotransmitters in the lizard parietal eye. Invest. Ophthalmol. Vis. Sci. 26: 676-678, 1985.

Battelle, B-A. and Evans, J. A.: Veratridine-stimulated release of amine conjugates from centrifugal fibers in the Limulus peripheral visual system.  J. Neurochem. 46: 1464-1472, 1986.

Chamberlain, S. C., Pepper, J., Battelle, B-A., Wyse, G. A., and Lewandowski, T. J.: Immunoreactivity in Limulus. II Studies of serotonin-like immunoreactivity, endogenous serotonin, and serotonin synthesis in the brain and lateral eye.  J. Comp. Neurol. 251: 363-375, 1986.

Engbretson, G. A. and Battelle, B-A.: Serotonin and dopamine in the retina of a lizard.  J. Comp. Neurol. 257: 140-147, 1987.

Evans, J. A. and Battelle, B-A.: Histogenesis of dopamine-containing neurons in the rat retina.  Exp. Eye Res. 44: 407-414, 1987.

Edwards, S. C. and Battelle, B-A.: Octopamine- and cAMP-stimulated phosphorylation of a protein in Limulus ventral and lateral eyes.  J. Neurosci. 7: 2811-2820, 1987.

Battelle, B-A., Edwards, S. C., Kass, L., Maresch, H. M., Pierce, S. K. and Wishart, A. C.: Identification and function of octopamine and tyramine conjugates in the Limulus visual system. J. Neurochem. 51: 1240-1251, 1988.

Edwards, S. C., Wishart, A. C., Wiebe, E. M., and Battelle, B-A.: Light-regulated proteins in Limulus.  Visual Neuroscience 3: 95-105, 1989.

Wiebe, E. M., Wishart, A. C., Edwards, S. C, and Battelle, B-A.: Ca++/calmodulin-stimulated phosphorylation of photoreceptor proteins in Limulus.  Visual Neuroscience 3: 107-118, 1989.

Orona, E., Battelle, B-A. and Ache, B. W.: Immunohistochemical and biochemical evidence for the putative inhibitory neurotransmitters, histamine and GABA, in lobster olfactory lobes. J. Comp. Neurol. 294: 633-646, 1990.

Edwards, S. C., Andrews, A. W., Renninger, G. H., Wiebe, E. M. and Battelle, B-A: Efferent innervation to Limulus eyes In Vivo phosphorylates a 122kD protein.  Biol. Bull. 178: 267-278, 1990.

Battelle, B-A.: Regulation of retinal functions by octopaminergic efferent neurons in Limulus Prog. Retinal Res. 10: 335-355, 1991.

Battelle, B-A., Calman, B. G., Andrews, A. W., Grieco, F. D., Mleziva, M. B., Callaway, J.C., and Stuart, A. E.: Histamine: A putative affernt neurotransmitter in Limulus eyes.  J. Comp. Neurol. 305: 527-542, 1991.

Calman, B. G., and Battelle, B-A.  Central origin of the efferent neurons projecting to the eyes of Limulus polyphemus. Visual Neuroscience 6:481-495, 1991.

Calman, B. G., Lauerman, M. A., Andrews, A. W., Schmidt, M. and Battelle, B-A.: Central projections of Limulus photoreceptor cells revealed by a photoreceptor-specific monoclonal antibody.  J. Comp. Neurol. 313:553-562, 1991.

Gaus, G., Doble, K.E., Price, D.A., Greenberg, M.J., Lee, T.D., and Battelle, B-A. The sequence of five neuropeptides isolated from Limulus using antisera to FMRFamide. Biol. Bull. 184:322-329, 1993.

Smith, W. C., Price, D. A., Greenberg, R. M., and Battelle, B-A.: Opsins from the lateral eyes and ocelli of the horseshoe crab, Limulus polyphemus. Proc. Nat’l. Acad. Sci. U.S.A. 90:6150-6154, 1993.

Zhang, H-J., Jinks, R. N., Andrews, A. W., Battelle, B-A., Chamberlain, S. C., Fahrenbach, W. H., and Kass, L. An enzymatically enhanced recording technique for Limulus ventral photoreceptors: Physiology, biochemistry, and morphology. Visual Neuroscience 11: 41-52, 1994.

Smith, S.C., Greenberg, R.M., Calman, B.G., Hendrix, M.M., Hutchinson, L., Donoso, L.A. and Battelle, B-A.: Isolation and expression of an arrestin cDNA from the horseshoe crab lateral eye. J. Neurochem. 64: 1-13, 1995.

O’Neill, P.J., Jinks, R.N., Herzog, E.D., Battelle, B-A., Kass, L., Renninger, G.H., and Chamberlain, S.C.: The morphology of the dorsal eye of the hydrothermal vent shrimp, Rimicaris exoculata. Visual Neuroscience 12: 861-875, 1995.

Renninger, G.H., Kass, L., Gleeson, R.A., VanDover, C.L., Battelle, B-A., Jinks, R.N., Herzog, E.D., and Chamberlain, S.C. Sulfide as a chemical stimulus for deep-sea hydrothermal vent shrimp. Biol. Bull. 189: 69-76, 1995.

Nuckley, D.J., Jinks, R.N., Battelle, B-A., Herzog, E.D., Kass, L., Renninger, G.H., and Chamberlain, S.C. Retinal anatomy of a new species of bresiliid shrimp from a hydrophermal vent fiels on the Mid-Atlantic Ridge. Bio. Bull. 190: 98-110, 1996.

Calman, B.G., Andrews, A.W., Edwards, S.C., Rissler. H.M., and Battelle, B-A. Calcium/calmoduilin-dependent protein kinase II and arrestin phosphorylation in Limulus eyes. J.Photochem. Photobiol. B. 35:33-44, 1996.

Munger, S.D., Schremser-Berlin, J.-L., Brink, C.M. and Battelle, B-A. Molecular and immunological characterization of a Gq protein from ventral and lateral eye of the horseshoe crab Limulus polyphemus. Invertebrate Neuroscience. 2:175-182, 1997.

Larkin, R.C., Jinks, R.N., Battelle, B-A., Herzog,E.D., Kass, L., Renninger, G., and Chans in mberlain, S.C. Retinal anatomy of Chorocaris chacei, a deep-sea hydrothermal vent shrimp from the Mid-Atlantic Ridge. J. Comp. Neurol. 385:503-514, 1997.

Kuenzler, R.O., Kwasniewski, J.T., Jinks, R.N., Larkin, R.C., Battelle, B-A., Herzog, E.D., Kass,L., Renninger, G.H., and Chamberlain, S.C. Retinal anatomy of new bresilid shrimp from the Lucky Strike and Broken Spur hydrothermal vent fields on the Mid-Atlantic Ridge. J. Mar. Bio. Assoc. (U.K.)  77:707-725, 1977.

Wharton, D.N., Jinks, R.N., Herzog, E.D., Battelle, B.A., Kass, L., Renninger, G.H., Chamberlain, S.C. Morphology of the eye of the hydrothermal vent shrimp, Alvinocaris markensis. Journal of the Marine Biological Association of the United Kingdom 77:1097-1108, 1997.

Jinks, R.N., Battelle, B.A., Herzog, E.D., Kass, L. Renninger, G.H. and Chamberlain, S.C. Sensory adaptations in hydrothermal vent shrimps from the Mid-Atlantic Ridge. Cah. Biol. Mar, 39: 309-312, 1998.

Battelle, B-A., Andrews, A.W., Calman, B.G., Sellers, J.R., Greenberg, R.M., and Smith, W.C. A myosin III from Limulus eyes is a clock-regulated phosphoprotein. J. Neurosci.  18:4548-4559, 1998.

Battelle, B-A., Calman, B.G., and Hart, M.K. Cellular distribution and functions of histamine, octopamine, and serotonin in the peripheral visual system, brain, and circumesophageal ring of the horseshoe crab Limulus polyphemus. Microscopy Res, and Tech.44:70-80, 1999.

Chen, F., Ukhanova, M., Thomas, D., Afshar, G., Tanda, S., Battelle, B-A., and Payne, R. Molecular cloning of a putative cyclic nucleotide-gated ion channel cDNA from Limulus polyphemus. J. Neurochem. 72:461-471, 1999.

Castanon-Cervantes, O., Battelle, B-A. and Fanjul-Moles, M.L. Rhythmic changes in the content of serotonin in the brain and eye stalks of crayfish during development. J. Exp. Biol. 202:2823-2830, 1999.

Battelle, B-A., Williams, C.D., Schremser-Berlin, J-L. and Cacciatore, C.  Regulation of arrestin mRNA levels in Limulus lateral eyes: Separate and combined influences of circadian efferent input and light.  Visual Neuroscience 17:217-227, 2000.

Battelle, B-A., Andrews, A.W., Kempler, K.E., Edwards, S.C., and Smith, S.C. Visual arrestin in Limulus is phosphorylated at multiple sites in the light and in the dark. Visual Neuroscience 17: 813-822, 2000.

Battelle, B-A., Dabdoub A, Malone, M.A., Andrews, A.W., Cacciatore, C., Calman, B.G., Smith, W.C., and Payne, R. Immunocytochemical localization of opsin, visual arrestin, myosin III, and calmodulin in Limulus lateral eye retinular cells and ventral photoreceptors. J. Comp. Neurol. 435:211-225, 2001.

Sacunas, R.B., Papuga, M.O., Malone, M.A., Pearson, A.C. Jr, Marjanovic, M., Stroope, D.G., Weiner, W.W., Chamberlain, S.C., Battelle, B-A. Multiple mechanisms of rhabdom shedding in the lateral eye of Limulus polyphemus.  J. Comp. Neurol. 449: 26-42, 2002.

Battelle, B-A. Circadian efferent input to Limulus eyes: Anatomy, circuitry and impact. Microscopy Res. and Tech. 58:345-355, 2002.

Battelle, B-A. and Hart, M.K. Histamine metabolism in the visual system of the horseshoe crab Limulus polyphemus.  Comp. Biochem. and Physiol. Part A 133:135-142, 2002.

Dabdoub, A., Jinks, R.N., Wang, Y., Battelle, B-A., and Payne, R. Desensitization of the photoresponse in Limulus ventral photoreceptors by protein kinase C precedes rhabdomere disorganization and endocytosis.Visual Neuroscience 20:241-248, 2003.

Dalal, J.S., Jinks, R.N., Cacciatore, C, Greenberg, R.M., and Battelle, B-A. Limulus opsins: Diurnal regulation and expression. Visual Neuroscience 20:523-534, 2003.

Sineschchekova, O.O., Cardasis, H.L., Severance, E.G., Smith, W.C., and Battelle, B-A. Sequential phosphorylation of visual arrestin in intact Limulus photoreceptors: Identification of a highly light-regulated site. Visual Neuroscience 21:715-724, 2004.

Harzsch, S., Wildt, M., Battelle, B., Waloszek, D. Immunohistochemical localization of neurotransmitters in the nervous system of larval Limulus polyphemus (Chelicerata, Xiphosura): evidence for a conserved protocerebral architecture in Euarthropoda. Arthropod Str. Devel.34:327-342, 2005.

Battelle, B-A. The eyes of Limulus polyphemus (Xiphosura, Chelicerata) and their afferent and efferent projections.  Arthropod Str. Devel.  35: 1-14, 2006.

Harzsch, S, Vilpoux, K., Blackburn, D. C., Platchetzki, D., Brown, N. L., Melzer, R., Kempler, K.E.  Battelle, B-A. Evolution of arthropod visual systems: Development of the eyes and central visual pathways in the horseshoe crab Limulus polyphemus Linnaeus, 1758 (Chelicerata, Xiphosura). Devel. Dynamics 235: 2641-2655, 2006.

Kempler, K., Toth, J., Yamashita, R., Mapel, G., Robinson, K., Cardasis, H., Stevens, S., Sellers, J.R. and Battelle, B-A. Loop 2 of Limulus myosin III is phosphorylated by protein kinase A and autophosphorylation. Biochemistry 46: 4280-4293, 2007.

Cardasis, H.L., Stevens, S.M., McClung, S., Kempler, K.E., Powell, D.H., Eyler, J.R., and Battelle, B-A. The actin-binding interface of a myosin III is phosphorylated in vivo in response to signals from a circadian clock. Biochemistry 46: 13907 – 13919, 2007.

Battelle, B-A. Circadian rhythms in visual function in Limulus. In Comparative Aspects of Circadian Rhythms. Eds. Marie Luisa Fanjul-Moles and Raul Aguilar-Roblero. Transworld Research Network 37/661 (2), 2008.

David C. Blackburn, Kevin W. Conley, David C. Plachetzki, Karen Kempler, Barbara-Anne Battelle and Nadean L. Brown. Isolation and expression of Pax6 and atonal homologues in the American Horseshoe Crab, Limulus polyphemus. Developmental Dynamics 237: 2209-2219, 2008.

Katti, C. Dalal, J. S, Dosé, A.C., Burnside, B and Battelle, B-A. Cloning and Distribution of Myosin 3B in the Mouse Retina: Differential Distribution in Cone Outer Segments. Experimental Eye Research 89, 224-237, 2009. PMCID: PMC2782900

Battelle, B-A. Limulus eyes and their circadian regulation. In Encyclopedia of the Eye, Vol. 2. Darlene A Dratt, editor, Oxford: Academic Press: pp 581-590: 2010.

Katti, C., Kempler, K., Porter, M.L., Legg, A., Gonzalez, R., Garcia-Rivera, E., Dugger, D., Battelle, B-A. Opsin co-expression in Limulus photoreceptors: Differential regulation by light and a circadian clock. J. Exp. Biol. 213 (Pt 15):2589-2601, 2010.

Dalal, J.S. and Battelle, B-A. Circadian regulation of Limulus visual functions: A role for octopamine and cAMP. Current Zoology 56(5):518-536, 2010.

Dalal, J.S., Stevens, Jr., S. M., Alverez, S., Munoz, N., Kempler, K.E., Dose, A.C., Burnside, B., Battelle, B-A. Mouse Class III kinases: Characterization of kinase activity and identification of phosphorylation sites. J. Neurochem. 19(4):772-84, 2011.

Battelle, B-A., Kempler, K.E., Parker, A.K., Gaddie C.D. Opsin1-2, Gqα and arrestin levels at Limulus rhabdoms are controlled by diurnal light and a circadian clock. J. Exp. Biol. 216(10):1837-1849, 2013.

Battelle, B-A. What the clock tells the eye: Lessons from an ancient arthropod. Integrative and Comparative Biology 53(1):144-53, 2013 doi: 10.1093/icb/ict020.

Battelle, B-A., Kempler, K.E., Harrison, A., Dugger, D. R., Payne, R. Opsin expression in Limulus eyes:  A UV opsin is expressed in each eye type and co-expressed with a visible light-sensitive opsin in ventral larval eyes. J Exp. Biol 217:3133-45. doi: 10.1242/jeb.107383. Epub 2014 Jun 19.

Daniel I. Speiser, M. Sabrina Pankey, Alexander K. Zaharoff, Barbara A. Battelle, Heather D. Bracken-Grissom, Jesse W. Breinholt, Seth M. Bybee, Thomas W. Cronin, Anders Garm, Nipam H. Patel, Megan L. Porter, Meredith E. Protas, Ajna S. Rivera, Jeanne M. Serb, Kirk S. Zigler, Keith A. Crandall, and Todd H. Oakley.  Using Phylogenetically-Informed Annotation (PIA) to search for light-interacting genes in transcriptomes from non-model organisms. BMC Bioinformatics. 2014 Nov 19;15(1):350. [Epub ahead of print]PMID: 25407802

B-A. Battelle, K.E. Kempler, S. R. Saraf, C. Marten, D. R. Dugger,  Jr., D.I. Speiser and T.H. Oakley. Opsins in Limulus eyes:  Characterization of three visible light sensitive opsins unique to and co-expressed in median eye photoreceptors and a peropsin/RGR expressed in all eyes. J Exp Biol. 2015 Feb 1;218(Pt 3):466-79. doi: 10.1242/jeb.116087. Epub 2014 Dec 18.  PMID: 25524988

Battelle, Barbara A., Sombke, Andy, Harzsch, Steffen. “Xiphosura” in Structure and Evolution of Invertebrate  Nervous Systems”  Oxford University Press  Editors: A. Schmidt-Rhaesa, S. Harzsch, G. Purschke. Pp 428-442. 2016.

Barbara-Anne Battelle, Joseph F. Ryan, Karen E. Kempler, Spencer R. Saraf, Catherine E. Marten, Wesley C. Warren, Patrick J. Minx, Michael J. Montague, Pamela J. Green, Skye A. Schmidt, Lucinda Fulton, Nipam H. Patel, Meredith E. Protas, Richard K. Wilson, and Megan L. Porter.  Opsin Repertoire and Expression Patterns in Horseshoe Crabs: Evidence from the Genome of Limulus polyphemus (Arthropoda: Chelicerata) Genome Biol Evol. 2016, 8:1571-1589.