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University of Florida

Publications

Leonid Moroz, Ph.D.

Recent & Relevant Publications: 2015-Present

(Out of >140 peer reviewed papers)
  • Norekian, T.P., Moroz, L.L. 2023. Recording cilia activity in ctenophores: effects of nitric oxide and low molecular weight transmitters. Front Neurosci 17, 1125476, p. 1-9. doi:10.3389/fnins.2023.1125476
  • Nikitin, M.A., Romanova, D.Y., Borman, S. I., Moroz, L.L. 2023. Amino acids integrate behaviors in nerveless placozoans. Front Neurosci 17, 1125624, p. 1-21. doi:10.3389/fnins.2023.1125624
  • Mukherjee, K., Moroz, L.L. 2023. Transposonderived transcription factors across metazoans. Front Cell Dev Biol 11, 1113046, p. 1-12. doi:10.3389/fcell.2023.1113046
  • Moroz, L.L., Romanova, D.Y. 2023. Chemical cognition: chemoconnectomics and convergent evolution of integrative systems in animals. Anim Cogn 26, p. 1851-1864, doi:10.1007/s10071-023-01833-7
  • Moroz, L.L., Romanova, D.Y. 2023. Homologous vs. homocratic neurons: revisiting complex evolutionary trajectories. Front Cell Dev Biol 11, 1336093, p. 1-6. doi:10.3389/fcell.2023.1336093
  • Moroz, L.L., Mukherjee, K., Romanova, D.Y. 2023. Nitric oxide signaling in ctenophores. Front Neurosci 17, 1125433, p.1-15. doi:10.3389/fnins.2023.1125433
  • Moroz, L.L. 2023. Syncytial nets vs. chemical signaling: emerging properties of alternative integrative systems. Front Cell Dev Biol 11, 1320209, p. 1-6. doi:10.3389/fcell.2023.1320209
  • Corrales, M., Cocanougher, B.T., Kohn, A.B., Wittenbach, J.D., Long, X.S., Lemire, A., Cardona, A., Singer, R.H., Moroz, L.L., Zlatic, M. 2022. A singlecell transcriptomic atlas of complete insect nervous systems across multiple life stages. Neural Dev 17:8
  • Dillon, N., Cocanougher, B., Sood, C., Yuan, X., Kohn, A.B., Moroz, L.L., Siegrist, S.E., Zlatic, M., Doe, C.Q. 2022. Single cell RNA-seq analysis reveals temporally-regulated and quiescence-regulated gene expression in Drosophila larval neuroblasts. Neural Dev 17:7
  • Drabkova, M., Kocot, K.M., Halanych, K.M., Oakley, T.H., Moroz, L.L., Cannon, J.T., Kuris, A., Garcia-Vedrenne, A.E., Pankey, M.S., Ellis, E.A., Varney, R., Stefka, J., Zrzavy, J. 2022. Different phylogenomic methods support monophyly of enigmatic ‘Mesozoa’ (Dicyemida +Orthonectida, Lophotrochozoa). Proc Biol Sci 289:20220683
  • Moroz, L.L., Romanova, D.Y. 2022. Alternative neural systems: What is a neuron? (Ctenophores, sponges and placozoans). Front Cell Dev Biol 10:1071961
  • Stern-Mentch, N., Bostwick, G.W., Belenky, M., Moroz, L.L. & Hochner, B. 2022. Neurotransmission and neuromodulation systems in the learning and memory network of Octopus vulgaris. J Morphol. p 1-28. DOI: 10.1002/jmor.21459
  • Romanova, D.Y., Nikitin, M.A., Shchenkov, S.V. & Moroz, L.L. 2022. Expanding of Life Strategies in Placozoa: Insights From Long-Term Culturing of Trichoplax and Hoilungia. Frontiers in Cell and Developmental Biology, 10, 1-15. DOI: 10.3389/fcell.2022.823283
  • Musser, J.M., Schippers, K.J., Nickel, M., Mizzon, G., Kohn, A.B., Pape, C., Ronchi, P., Papadopoulos, N., Tarashansky, A.J., Hammel, J.U., Wolf, F., Liang, C., Hernandez-Plaza, A., Cantalapiedra, C.P., Achim, K., Schieber, N.L., Pan, L., Ruperti, F., Francis, W.R., Vargas, S., Kling, S., Renkert, M., Polikarpov, M., Bourenkov, G., Feuda, R., Gaspar, I., Burkhardt, P., Wang, B., Bork, P., Beck, M., Schneider, T.R., Kreshuk, A., Worheide, G., Huerta-Cepas, J., Schwab, Y., Moroz, L.L. & Arendt, D. 2021. Profiling cellular diversity in sponges informs animal cell type and nervous system evolution. Science, 374, 717-723. DOI: 10.1126/science.abj2949
  • Stern-Mentch, N., Bostwick, G.W., Belenky, M., Moroz, L.L. & Hochner, B. 2022. Neurotransmission and neuromodulation systems in the learning and memory network of Octopus vulgaris. J Morphol. p 1-28. DOI: 10.1002/jmor.21459
  • Romanova, D.Y., Nikitin, M.A., Shchenkov, S.V. & Moroz, L.L. 2022. Expanding of Life Strategies in Placozoa: Insights From Long-Term Culturing of Trichoplax and Hoilungia. Frontiers in Cell and Developmental Biology, 10, 1-15. DOI: 10.3389/fcell.2022.823283
  • Gyori, J., Kohn, A.B., Romanova, D.Y. & Moroz, L.L. 2021. ATP signaling in the integrative neural center of Aplysia californica. Sci Rep, 11, 5478, p. 1-11. DOI: 10.1038/s41598-021-84981-5
  • Hoencamp, C., Dudchenko, O., Elbatsh, A.M.O., Brahmachari, S., Raaijmakers, J.A., van Schaik, T., Sedeno Cacciatore, A., Contessoto, V.G., van Heesbeen, R., van den Broek, B., Mhaskar, A.N., Teunissen, H., St Hilaire, B.G., Weisz, D., Omer, A.D., Pham, M., Colaric, Z., Yang, Z., Rao, S.S.P., Mitra, N., Lui, C., Yao, W., Khan, R., Moroz, L.L., Kohn, A., St Leger, J., Mena, A., Holcroft, K., Gambetta, M.C., Lim, F., Farley, E., Stein, N., Haddad, A., Chauss, D., Mutlu, A.S., Wang, M.C., Young, N.D., Hildebrandt, E., Cheng, H.H., Knight, C.J., Burnham, T.L.U., Hovel, K.A., Beel, A.J., Mattei, P.J., Kornberg, R.D., Warren, W.C., Cary, G., Gomez-Skarmeta, J.L., Hinman, V., Lindblad-Toh, K., Di Palma, F., Maeshima, K., Multani, A.S., Pathak, S., Nel-Themaat, L., Behringer, R.R., Kaur, P., Medema, R.H., van Steensel, B., de Wit, E., Onuchic, J.N., Di Pierro, M., Lieberman Aiden, E. & Rowland, B.D. 2021. 3D genomics across the tree of life reveals condensin II as a determinant of architecture type. Science, 372, 984-989. DOI: 10.1126/science.abe2218
  • Polinski, J.M., Zimin, A.V., Clark, K.F., Kohn, A.B., Sadowski, N., Timp, W., Ptitsyn, A., Khanna, P., Romanova, D.Y., Williams, P., Greenwood, S.J., Moroz, L.L., Walt, D.R. & Bodnar, A.G. 2021. The American lobster genome reveals insights on longevity, neural, and immune adaptations. Science Advances, 7, 1-5. DOI: 10.3389/fcell.2022.823283
  • Moroz, L.L. 2021. Multiple Origins of Neurons From Secretory Cells. Front Cell Dev Biol, 9, 669087, 1-9. DOI: 10.3389/fcell.2021.669087
  • Moroz, L.L., Nikitin, M.A., Policar, P.G., Kohn, A.B. & Romanova, D.Y. 2021a. Evolution of glutamatergic signaling and synapses. Neuropharmacology, 199, 108740, p. 1-31. DOI: 10.1016/j.neuropharm.2021 Moroz, L.L. & Romanova, D.Y. 2021. Selective Advantages of Synapses in Evolution. Front Cell Dev Biol, 9, 726563., p. 1-8. DOI: 10.3389/fcell.2021.726563
  • Moroz, L.L., Romanova, D.Y. & Kohn, A.B. 2021b. Neural versus alternative integrative systems: molecular insights into origins of neurotransmitters. Philos Trans R Soc Lond B Biol Sci, 376, 20190762, 1-22. DOI: 10.1098/rstb.2019.0762
  • Norekian, T.P. & Moroz, L.L. 2021. Development of the nervous system in the early hatching larvae of the ctenophore Mnemiopsis leidyi. J Morphol, 282, 1466-1477. doi: 10.1002/jmor.21398
  • Romanova, D.Y., Varoqueaux, F., Daraspe, J., Nikitin, M.A., Eitel, M., Fasshauer, D. & Moroz, L.L. 2021. Hidden cell diversity in Placozoa: ultrastructural insights from Hoilungia hongkongensis. Cell Tissue Res, 385, 623-637. DOI: 10.1007/s00441-021-03459-y
  • Moroz, L. L., Romanova, D. Y., Nikitin, M. A., Sohn, D., Kohn, A. B., Neveu, E., Varoqueaux, F. & Fasshauer, D. 2020 The diversification and lineage-specific expansion of nitric oxide signaling in Placozoa: insights in the evolution of gaseous transmission. Sci Rep 10, 13020. (DOI:10.1038/s41598- 020-69851-w).
  • Moroz, L. L., Sohn, D., Romanova, D. Y. & Kohn, A. B. 2020 Microchemical identification of enantiomers in early-branching animals: Lineage-specific diversification in the usage of D-glutamate and D-aspartate. Biochem Biophys Res Commun 527, 947-952. (DOI:10.1016/j.bbrc.2020.04.135).
  • Norekian, T. P. & Moroz, L. L. 2020. Atlas of the neuromuscular system in the Trachymedusa Aglantha digitale: Insights from the advanced hydrozoan. J Comp Neurol 528, 1231-1254. (DOI:10.1002/cne.24821).
  • Romanova, D. Y., Heyland, A., Sohn, D., Kohn, A. B., Fasshauer, D., Varoqueaux, F. & Moroz, L. L. 2020. Glycine as a signaling molecule and chemoattractant in Trichoplax (Placozoa): insights into the early evolution of neurotransmitters. Neuroreport 31, 490-497. (DOI:10.1097/WNR.0000000000001436).
  • Romanova, D. Y., Smirnov, I. V., Nikitin, M. A., Kohn, A. B., Borman, A. I., Malyshev, A. Y., Balaban, P. M. & Moroz, L. L. 2020. Sodium action potentials in placozoa: Insights into behavioral integration and evolution of nerveless animals. Biochem Biophys Res Commun 532, 120-126. (DOI:10.1016/j.bbrc.2020.08.020).
  • Winters, G. C., Polese, G., Di Cosmo, A. & Moroz, L. L. 2020. Mapping of neuropeptide Y expression in Octopus brains. J Morphol 281, 790-801. (DOI:10.1002/jmor.21141).
  • Li, X., Feng, K., Li, L., Yang, L., Pan, X., Yazd, H. S., Cui, C., Li, J., Moroz, L.L, Sun, Y., et al. 2020. Lipid–oligonucleotide conjugates for bioapplications. National Science Review 7, 1933–1953. (DOI:10.1093/nsr/nwaa161).
  • Moroz, L. L., Romanova, D. Y. & Kohn, A. B. 2020. Neural versus alternative integrative systems: Molecular insights into origins of neurotransmitters. Phil. Trans. R. Soc. B B 20190762, 1-22. (DOI:10.1098/rstb.2019.0762).
  • Cocanougher, B.T., Wittenbach, J.D., Long, X.S., Kohn, A.B., Norekian, T.P., Yan, J., Colonell, J., Masson, J-B., James W. Truman, J. W., Cardona, A., Turaga, S.C., Singer, R.H., Moroz, L.L., Zlatic, M. 2020. Comparative single-cell transcriptomics of complete nervous systems. eLife.
  • Norekian, T.P., Moroz, L.L. 2020. Comparative neuroanatomy of ctenophores: Neural and muscular systems in Euplokamis dunlapae and related species. The Journal of Comparative Neurology 528(3):481-501. doi: 10.1002/cne.24770.
  • Orlov, Y.L., Baranova, A.V., Kolchanov, N.A., Moroz, L.L. 2019. Evolutionary biology and biodiversity research at BGRS-2018. BMC Evolutionary Biology. 2019; 19(Suppl 1):43. doi: 10.1186/s12862-019-1368-5.
  • Zverkov, O.A., Mikhailov, K.V., Isaev, S.V., Rusin, L.Y., Popova, O.V., Logacheva, M.D., Penin, A.A., Moroz, L.L., Panchin, Y.V., Lyubetsky, V.A., Aleoshin, V.V. 2019. Dicyemida and Orthonectida: Two Stories of Body Plan Simplification. Frontiers in Genetics. 2019 10:443. doi: 10.3389/fgene.2019.00443.
  • Norekian, T.P., Moroz, L.L. 2019. Atlas of the neuromuscular system in the Trachymedusa Aglantha digitale: Insights from the advanced hydrozoan. The Journal of Comparative Neurology doi.org/10.1002/cne.24821
  • Norekian, T.P., Moroz, L.L. 2019. Neuromuscular organization of the Ctenophore Pleurobrachia bachei. The Journal of Comparative Neurology 527(2):406-436. doi.org/10.1002/cne.24546
  • Norekian, T.P., Moroz, L.L. 2019. Neural system and receptor diversity in the ctenophore Beroe abyssicola. The Journal of Comparative Neurology 527(12):1986-2008. doi.org/10.1002/cne.24633
  • Norekian, T.P., Moroz, L.L. 2019 (Epub). Comparative neuroanatomy of ctenophores: Neural and muscular systems in Euplokamis dunlapae and related species. The Journal of Comparative Neurology 2020.528(3):481-501. doi: 10.1002/cne.24770.
  • Moroz, L.L. (2018). NeuroSystematics and Periodic System of Neurons: Model vs Reference Species at Single-Cell Resolution. ACS Chemical Neuroscience 9, 1884−1903.
  • Moroz, L.L., Norekian, T.P. (2018). Atlas of Neuromuscular Organization in the Ctenophore, Pleurobrachia bachei (A. Agassiz, 1860). Biorxiv, doi: https://doi.org/10.1101/385435 http://orcid.org/0000-0002-1333-3176 
  • Whelan, Nathan V., Kocot, Kevin M., Moroz, Tatiana P., Mukherjee Krishanu, Williams, Peter, Paulay, Gustav, Moroz, L.L. and Kenneth M. Halanych. (2017). Ctenophore relationships and their placement as the sister group to all other animals. Nature Ecology & Evolution, Vol 1,1737–1746. doi: 10.1038/s41559-017-0381-6.
  • Adema, Coen M., Moroz, L.L., et al. (2017). Whole genome analysis of a schistosomiasis transmitting freshwater snail. Nature Communications Vol. 8:15451; 1-12. | DOI: 10.1038/ncomms15451.
  • Kocot KM, Struck TH, Merkel J, Waits DS, Todt C, Brannock PM, Weese DA, Cannon JT, Moroz L.L., Lieb B., Halanych K.M. (2017). Phylogenomics of Lophotrochozoa with Consideration of Systematic Error. Systematic Biology. Vol. 66(2):256-282. doi: 10.1093/sysbio/syw079.
  • Moroz, L.L., Halanych, K.M. (2016) Evolution: A sisterly dispute. Nature 529(7586):286-7. doi:10.1038/529286a
  • Moroz LL, Kohn, AB. (2016). Independent origins of neurons and synapses: insights from ctenophores. Phil. Trans. R. Soc. B. 2016; 371 (1685), 20150041
  • Halanych K M, Whelan, NV, Kocot KM, Kohn AB, Moroz, LL (2016). Miscues misplace sponges. Proc. Natl. Acad. Sci. U S A, 13(8):E946-7.
  • Norekian TP, Moroz LL. (2016). Development of neuromuscular organization in the ctenophore, Pleurobrachia bachei. J. Comp. Neurol.; 524, 136-151.
  • Moroz LL, Halanych KM. (2016). Evolution: Methodological Misconceptions. Nature 529, 286-287.
  • Whelan NV, Kevin M. Kocot KM, Moroz LL, Halanych KM. (2015). Error, signal, and the placement of Ctenophora sister to all other animals. Proc. Natl. Acad. Sci. USA; 112, 5773-5778.
  • Moroz LL. (2015). Biodiversity Meets Neuroscience: From the Sequencing Ship (Ship-Seq) to Deciphering Parallel Evolution of Neural Systems in Omic’s Era. Integr. Comp. Biol.; 55, 1005-1017.
  • Moroz LL, Kohn AB. (2015). Unbiased View of Synaptic and Neuronal Gene Complement in Ctenophores: Are There Pan-neuronal and Pan-synaptic Genes across Metazoa? Integr. Comp.  Biol.; 55, 1028-1049.
  • Yang Q, Kuzyk P, Antonov I, Bostwick C, Kohn AB, Moroz LL, Hawkins RD. (2015). Hyperpolarization-activated, cyclic nucleotide-gated cation channels in Aplysia. Proc. Natl. Acad. Sci. USA; 112:16030-16035
  • Yoshida MA, Ogura A, Ikeo K, Shigeno S, Moritaki, Winters GC, Kohn AB Moroz LL. (2015).
    Molecular evidence for convergence and parallelism in evolution of complex brains of cephalopod molluscs: Insights from visual systems. Integr. Comp. Biol.; 55, 1070-1083.
  • Kohn AB, Sanford R, Yoshida M-a, Moroz LL. (2015). Parallel Evolution and Lineage-Specific Expansion of RNA Editing in Ctenophores. Integr. Comp. Biol.; 55, 1111-1120.
  • Dabe EC, Sanford RS, Kohn AB, Bobkova Y, Moroz LL. (2015). DNA Methylation in Basal Metazoans: Insights from Ctenophores. Integr. Comp. Biol.; 55, 1096-1110.
  • Moroz LL, Kohn AB. (2015). Analysis of gene expression in neurons and synapses by multi-color in situ hybridization. Neuromethods; v. 99, 293-317.
  • Moroz LL. (2015). Convergent evolution of neural systems in ctenophores. J. Experimental Biology. 2015; 218, 1-13. doi:10.1242/jeb.110692.