Recent Publications (2010-Present)

Lanza, A. R. and Seaver, E. C. (2020). Functional role for activin/Nodal signaling in establishment of the dorsal-ventral axis in the spiralian annelid Capitella teleta. Development 147: dev189373 doi:10.1242/dev.189373

Wu, L., Hiebert, L.S., Klann, M., Passamaneck, Y., Bastin, B. R., Schneider, S. Q., Martindale, M. Q., Seaver, E. C., Maslakova, S. A., and Lambert, J. D. Genes with spiralian-specific protein motifs are expressed in spiralian ciliary bands. Nat Commun 11, 4171 (2020).

Lanza, A. R. and Seaver, E. C. (2020) Activin/Nodal signaling mediates dorsal-ventral axis formation before third quartet formation in embryos of the annelid Chaetopterus pergamentaceous. EvoDevo 11:17.

Klann, M. and Seaver, E. C. (2019). Distinct functional roles of the paired domain and homeodomain of pax6 in eye and nervous system development in the annelid Capitella teleta. Developmental Biology 456 (1): 86-103.

Neal, S., de Jong, D. M. and Seaver, E. C. (2019). CRISPR/Cas9 mutagenesis of r-opsin blocks phototaxis in a marine larva. Proc. R. Soc. B 286: 20182491.

Dannenberg, L.C. and Seaver, E.C. (2018). Regeneration of the germline in the annelid Capitella teleta. Developmental Biology 440(2):74-87.

Lanza, A.R. and Seaver, E.C. (2018). An organizing role for the TGF-β signaling pathway in axes formation of the annelid Capitella teleta. Developmental Biology 435 (1): 26- 40. *This article was selected for the cover image.

de Jong, D. M. and Seaver, E. C. (2017). ­­Investigation into the cellular origins of posterior regeneration in the annelid Capitella teleta. Regeneration 00:1-17. DOI: 10.1002/reg2.94

Sur, A., Magie, C. R., Seaver, E. C. and Meyer, N. P. (2017). Spatiotemporal regulation of nervous system development in the annelid Capitella teleta. EvoDevo 8:13(

Seaver, E. C. (2017). Annelids shed light on the evolution of spiralian development. Canadian Journal of Zoology (

Seaver, E. C. Annelid models I: Capitella teleta (2016). Current Opinion in Genetics and Development 39: 35–41.

de Jong, D.M., Seaver, E.C. (2016) A Stable Thoracic Hox Code and Epimorphosis Characterize Posterior Regeneration in Capitella teleta. PLOS ONE 11(2): e0149724. doi: 10.1371/journal.pone.0149724

Yamaguchi*, E., and Seaver, E. C. (2016) Regulative capacity for eye formation by first quartet micromeres of the polychaete Capitella teleta. Developmental Biology 410 (1): 119 – 130. (doi: 10.1016/j.ydbio.2015.12.009).

Meyer, N. P., Carrillo-Baltodano, A, Moore*, R. E. and Seaver, E. C. (2015) Nervous system development in lecithotrophic larval and juvenile stages of the annelid Capitella teleta. Frontiers in Zoology 12: 15 (doi:10.1186/s12983-015-0108-y).

Seaver, E. C. (2014). Variation in spiralian development: insights from polychaetes. International Journal of Developmental Biology 58: 457-467. 10.1387/ijdb.140154es.

Boyle*, M. J., Yamaguchi*, E. and Seaver, E. C. (2014). Molecular conservation of metazoan gut formation: Evidence from expression of ‘endomesoderm genes’ in Capitella teleta (Annelida) EvoDevo 5: 39.

Yamaguchi*, E., and Seaver, E. C. (2013). The importance of larval eyes in the polychaete Capitella teleta: effects of eye deletion on formation of the adult eye. Invertebrate Biology 132 (4): 352-367 (doi: 10.1111/ivb.12034).

Amiel, A., Henry, J. Q. and Seaver, E. C. (2013). An organizing activity is required for head patterning and cell fate specification in the polychaete annelid Capitella teleta: new insights into cell-cell signaling in Lophotrochozoa. Developmental Biology 379: 107-122 (doi: 10.1016/j.ydbio.2013.04.011).

Simakov, O., Marletaz, F., Cho, S.-J., Edsinger-Gonzales, E., Havlak, P., Hellsten, U., Kuo, D.-H., Larsson, T., Lv, J., Arendt, D., Savage, R., Osoegawa, K., de Jong, P., Grimwood, J., Chapman, J. A., Shapiro, H., Kuo, A., Otillar, R. P., Terry, A. Y., Boore, J. L., Grigoriev, I. V., Lindberg, D. R., Seaver, E. C., Weisblat, D. A., Putnam, N. H., Rokhsar, D. S. (2013). Insights into bilaterian evolution from three spiralian genomes. Nature 493(7433): 526-531 (doi: 10.1038/nature11696.).

Pernet, B., Amiel, A. and Seaver, E. C. (2012). Effects of maternal investment on larvae and juveniles of the annelid Capitella teleta determined by experimental reduction of embryo energy content. Invertebrate Biology 131(2): 82-95 (DOI: 10.111/j.1744-7410.2012.00263.x).

Seaver, E. C., Yamaguchi, E*. Richards, G. S. and Meyer, N. P. (2012). Expression of the pair-rule gene homologues runt, Pax3/7, even-skipped-1 and even-skipped-2 during larval and juvenile development of the polychaete annelid Capitella teleta does not support a role in segmentation. EvoDevo 3:8.

Giani*, V. C. Jr., Yamaguchi, E. and Seaver, E. C. (2011). Somatic and germ line expression of piwi throughout the life cycle of the polychaete annelid Capitella teleta. EvoDevo 2:10.

Jackson, D. J., Meyer, N. P., Seaver, E. C., Pang K., McDougall, C., Moy, V. N., Gordon, K., Degnan, B. M., Martindale, M. Q., Burke, R. and Peterson, K. J. (2010). Developmental expression of COE across the Metazoa supports a conserved role in neuronal cell-type specification and mesodermal development. Development, Genes and Evolution 220:221-234.

Layden, M. J., Meyer N. P., Pang K., Seaver, E. C. and Martindale, M. Q. (2010). Expression and phylogenetic analysis of the zic gene family in the evolution and development of metazoans. EvoDevo 1:12.

Meyer, N. P., Boyle*, M. J., Martindale, M. Q. and Seaver, E. C. (2010). A comprehensive fate map by intracellular injection of identified blastomeres in the marine polychaete Capitella teleta. EvoDevo 1:8.

Meyer, N. P. and Seaver, E. C. (2010). Cell lineage and fate map of the primary somatoblast of the polychaete annelid Capitella teleta. Integrative and Comparative Biology 50(5):756-67.

Boyle*, M. J. and Seaver, E. C. (2010). Expression of FoxA and GATA transcription factors correlates with regionalized gut development in two lophotrochozoan marine worms: Chaetopterus (Annelida) and Themiste lageniformis (Sipuncula). EvoDevo 1:2.

Cho, S.-J., Valles, Y., Giani*, V. C., Seaver, E. C. and Weisblat, D. A. (2010). Evolutionary dynamics of the Wnt gene family: a lophotrochozoan perspective. Molecular Biology and Evolution 27(7): 1645-1658 doi:10.1093/molbev/msq052.

Shimeld, S. M., Boyle*, M. J., Brunet, T., Luke, G. N. and Seaver, E. C. (2010). Clustered Fox genes in lophotrochozoans and the evolution of the bilaterian Fox gene cluster. Developmental Biology 340: 234-248.